Funding Research to Make a Difference

KICKBALL REGISTRATION

The Be Brave for Life Foundation works to improve the quality of life for those affected by cavernous malformations and non-cancerous brain tumors by raising awareness and funding innovative research. Together, we will make difference for patients and families!

 

Riley's Story

Riley Callen founded Be Brave for Life in 2012. Here is her story.

Improving Research - Apply for a Grant

Applications for 2019 Micro-grants are due June 15, 2019.

Be Brave and Shop

Buy Be Brave Hats, T-shirts and Nalgene water bottles

Join the fight! Take action today.

As you raise funds to create awareness around and support research for cavernous malformations and non-cancerous brain tumors, you will discover the power that comes from being brave!

Want to be a part of the solution? See how to become an ambassador or a volunteer.
Volunteer & Leadership Opportunities

Surgery. The only cure for Cerebral Cavernous Malformation (CCM).

While four decades of research into CCM has resulted in a greater understanding of the growth of these lesions, treatment options remain limited. Today, they CANNOT be directly treated with medicine. Without surgery, symptoms can only be managed or monitored. The risks of surgery are high. It can cause permanent neurological deficits, especially in the brainstem, and there is still a high chance of recurrence.

Learn More

Our Sponsors

We're incredibly grateful to all of our supporters!
(and to Baxter - who hiked 50 mountains this summer in support.)

Become a Sponsor

Recent Blog Posts

Read about how we're working to fund research for a cure!

Tamela

I am Tamela Wagner, also known as Tamela Blessed Art. A creator of hope and happiness! My life changed in the blink of an eye when I was diagnosed in 2011 at age 44 with a rare brain disease called Cavernous Angioma. In 2012 I had brainstem surgery that many surgeons told me would be…

April 19, 2019

Erin

My name is Erin and I am a cavernous malformation survivor. In 2013 [during] my senior year of college…I drove seven hours home for spring break. That Monday, not even 3 days home, I got very sick… All of a sudden it felt like spiders were on my back and [my parents] called 911. [In the…

April 19, 2019

The role of Adamts in Cerebral Cavernous Malformation (CCM) disease

In the project above, I planned to test whether genetically and pharmacologically inhibiting Adamts in CCM disease can be utilised as a therapeutic target for Cerebral Cavernous Malformations (CCMs). Since I received the grant, I have identified an FDA approved drug, Ponatinib, which can effectively target MEKK3-KLF-ADAMTS pathway to prevent CCM formation and growth in…

April 15, 2019